Introduction: key roles in learning, memory and attention in humans is long, so that people are constantly seeking ways Which strengthens memory and reduce its deficit to pull up The effects of Nigella sativa extract on learning and memory in adult male rats was studied.Material and METHODS: This was an experimental study. For this 40 sar purpose, adult male Wistar rats weighing 220-180 g were divided into 5 groups of 8 And control groups, control). (The control group received nothing, 1/.0 ad lib controls ml normal saline gavage, is administered). Experimental groups 1, 2 3 daily doses of 100, 200 and 400 mg kg body weight extract of Nigella 17 days of receiving And then after 12 day get started learning extracts and extract operation is performed simultaneously with training and probe trial on day 18 without prescription extract is Barnes Maze taken from animals. The study was time delay for the purpose of this to evaluate the error number..Rresults: The results of this study showed that Nigella sativa significantly compared to the control groups Thereby increasing the learning and spatial memory.: (P<0.05). Conclusions: The results demonstrated that administration of Nigella sativa seed extract, oleic acid and linoleic acid antioxidant inflammation due to spatial memory is enhanced.

In order to study the effects of water stress and municipal compost on qualitative and quantitative characteristics of Nigella sativa this experiment was conducted in 2012 at the Agricultural Research Station of University of Zabol, Iran in a complete randomized block in split plot design with three replications. Treatments included irrigation intervals: 1. Every seven days (Without stress) 2. Every nine days (mild stress) and 3. Every twelve days (severe stress) and municipal compost treatment include: without municipal compost application (control), 10, 20 and 30 tons per hectare. The results showed that the effect of water stress was significant on the biological and seed yield, proline and chlorophyll (a). Also biological yield, grain yield and chlorophyll (a) decreased in water stress condition. But proline content in leaves increased with increasing stress level. According to results highest biological yield, grain yield, essential oil percentage, proline, chlorophyll a, chlorophyll b, total chlorophyll and carotenoids were obtained In municipal compost application. The Interaction between water stress and municipal compost treatments on chlorophyll a, chlorophyll b, total chlorophyll and carotenoid were significant. According to results the best treatment at the increase on seed yield and essential oil content were application 30 tons per hectares of municipal compost in Zabol weather conditions.

Salinity is an increasing problem in the world. Study of salt tolerance in medicinal plants is very important due to cultivation in saline lands. An experiment was carried out using a completely in randomized design in order to study the effect of salinity on Nigella saliva (Mashhad accession) in hydroponic condition with four replications in germination stage and with three replications in seedling stage. Salinity levels included 0 (control), 50, 100, 150 and 200 molm-3 sodium choride. The results showed significant differences for germination, vigority, root length, shoot length, root dry weight, shoot dry weight, shoot/root weight ratio, and biomass according to the increased salinity in N.saliva accession. N.saliva showed a higher tolerance to increased salinity level in seedling stage compared to germination stage.

Nigella sativa (NS) (Ranunculaceae family) is generally utilized as a therapeutic plant all over the world. The seeds of the plant have a long history of use in different frameworks of medicines and food. In Islamic literature, it is considered as one of the greatest forms of therapeutics. It has been widely used to treat nervous system diseases such as memory impairment, epilepsy, neurotoxicity, pain, etc. Additionally, this is uncovered that the majority of therapeutic properties of this plant are due to the presence of thymoquinone (TQ) which is a major bioactive component of the essential oil. Pharmacological studies have been done to evaluate the effects of NS on the central nervous system (CNS). The present review is an effort to provide a detailed scientific literature survey about pharmacological activities of the plant on nervous system. Our literature review showed that NS and its components can be considered as promising agents in the treatment of nervous system disorders.

Extended abstract Introduction: Deterioration reduces the quality of seeds. Oilseeds like Nigella are highly susceptible to seed aging. Seed priming enhances the quality of deteriorated seeds by improving germination indices and increasing the activity of antioxidant enzymes. This research aimed to investigate the extent of damage caused by accelerated aging treatment on the germination characteristics and antioxidant enzyme activity of Nigella seeds and the possibility of mitigating the adverse effects of aging through hormonal priming with cytokinin. Materials and methods: This research was carried out in the form of a completely random basic design with four replications in the seed technology laboratory of Khuzestan University of Agricultural Sciences and Natural Resources in 2017. The treatments included hormonal priming with cytokinin at five levels (0 (control), 10, 20, 40, and 80 m/l) for two durations (12 and 24 hours), and aging under 100% relative humidity and a temperature of 45 °C at five levels (no aging, 24, 48, 72, and 96 h). Results: The analysis of variance results indicated that germination indices were only influenced by main and two-way effects at the 5% and 1% probability levels, while the three-way interactions, including aging, hormone concentration, and priming duration, were significant for plant growth and longitudinal and weight indices at the 1% probability level. Furthermore, it was evident that the priming treatment mitigated the negative effects of aging, with the concentration of 10 milligrams per liter of cytokinin for a duration of 12 h having the most significant impact among the hormone concentrations used on the measured traits. The highest germination percentage (88%) and the lowest germination percentage (63.33%) were observed at concentrations of 10 and 80 mg/l, respectively. The use of cytokinin at optimal concentration improved catalase activity and protein levels. The results showed that in the control conditions, the activity of the catalase enzyme was 0.76 units per mg of protein and the amount of protein was 0.51 mg/g, which reached 0.97 units per mg of protein and 0.79 mg/g with seed priming. Conclusion: Based on the results obtained from this research, aging led to a reduction in germination indices, the activity of antioxidant enzymes, and seed protein content. The best treatment applied was cytokinin hormone priming for aged Nigella seeds at a concentration of 10 mg/l for 12 h. According to the results, the application of cytokinin at its optimal concentration (10 mg/l) improved the catalase enzyme activity and protein content. Therefore, it can be suggested that hormonal priming with cytokinin helps mitigate the adverse effects of aging in Nigella plants. Highlights: The impact of hormonal priming with cytokinin at concentrations of 10, 20, 40, and 80 mg/L on aged Nigella seeds was investigated. The use of a concentration of 10 mg/l of cytokinin hormone for 12 hours was introduced as the best treatment. Cytokinin was introduced as a significant hormone that enhances the activity of antioxidant enzymes and physiological traits in aged Nigella seeds.